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Scientific Studies Showing Cannabis Kills Cancer Cells
By: Lincoln Horsley
11/26/2013 Creator of cureyourowncancer.org In this day and age most people that hear about a "natural" treatment for cancer believe there is no way it can work. Most people have been brainwashed over the past 35 years to believe that modern medicine and all of its chemical drugs, like chemotherapy and radiation, are the only ways to treat cancer. I want you to know that this is not the case. Cannabinoids in cannabis, such as THC and CBD, have been shown to have anti cancer effects. These effects have been known about by the United States government for over 30 year. In 1974 researchers the Medical College of Virginia was funded by the National Institute of Health to find evidence that cannabis caused damage to the immune system. During their studies they found instead that THC slowed the growth of three kinds of cancer in mice; lung cancer, breast cancer, and a virus-induced leukemia. You would think this new research would have sparked major interest in cannabis to treat cancer, but this was not the case. Two years later in 1976 President Gerald Ford put an end to all public cannabis research and granted exclusive cannabis research rights to major pharmaceutical companies*. The goal of the pharmaceutical companies was to develop synthetic forms of THC that would deliver all the medical benefits without the "high". They were completely unsuccessful with this. |
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In September of 1983 the Reagan/Bush Administration tried to persuade American universities and researchers to destroy all research work done on cannabis from 1966-76*. The Reagan/Bush Administration requested works to be destroyed including compendiums in libraries. Scientists and doctors opposed this censorship so the plans were dropped. In his book "The Emperor Wears No Clothes" Jack Herer states, "We know that large amounts of information have since disappeared." Since the 1974 Virginia study there have been numerous other studies done all over the world showing the anti-cancer effects of cannabis. You may not have heard of these studies done showing the anti-cancer effects of cannabis so on this page I have compiled a list of articles on that subject. This page has articles containing over 40 different links to scientific studies showing the anti-cancer effects of cannabis. *Source: The Emperor Wears No Clothes by Jack Herer |
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Cannabis Shrinks Tumors: Government has known since 1974By: Raymond Cushing May 30th, 2000 RE-Print from Alternet.org In 1974 researchers learned that THC, the active chemical in cannabis, shrank or destroyed tumors in test mice. But the DEA quickly shut down the study and destroyed its results, which were never replicated -- until now. The term medical marijuana took on dramatic new meaning in February, 2000 when researchers in Madrid announced they had destroyed incurable brain tumors in rats by injecting them with THC, the active ingredient in cannabis. The Madrid study marks only the second time that THC has been administered to tumor-bearing animals; the first was a Virginia investigation 26 years ago. In both studies, the THC shrank or destroyed tumors in a majority of the test subjects. Most Americans don't know anything about the Madrid discovery. Virtually no major U.S. newspapers carried the story, which ran only once on the AP and UPI news wires, on Feb. 29, 2000. The ominous part is that this isn't the first time scientists have discovered that THC shrinks tumors. In 1974 researchers at the Medical College of Virginia, who had been funded by the National Institute of Health to find evidence that cannabis damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice -- lung and breast cancer, and a virus-induced leukemia. The DEA quickly shut down the Virginia study and all further cannabis/tumor research, according to Jack Herer, who reports on the events in his book, "The Emperor Wears No Clothes." In 1976 President Gerald Ford put an end to all public cannabis research and granted exclusive research rights to major pharmaceutical companies, who set out -- unsuccessfully -- to develop synthetic forms of THC that would deliver all the medical benefits without the "high." The Madrid researchers reported in the March issue of "Nature Medicine" that they injected the brains of 45 rats with cancer cells, producing tumors whose presence they confirmed through magnetic resonance imaging (MRI). On the 12th day they injected 15 of the rats with THC and 15 with Win-55,212-2 a synthetic compound similar to THC. "All the rats left untreated uniformly died 12-18 days after glioma (brain cancer) cell inoculation ... Cannabinoid (THC)-treated rats survived significantly longer than control rats. THC administration was ineffective in three rats, which died by days 16-18. Nine of the THC-treated rats surpassed the time of death of untreated rats, and survived up to 19-35 days. Moreover, the tumor was completely eradicated in three of the treated rats." The rats treated with Win-55,212-2 showed similar results. Study shows non-psychedelic cannabinoids in cannabis are effective anti-cancer drugsRE-PRINT: From the St. George University of London 14 October 2013 New research has shown that the non-psychedelic components of cannabis could act as effective anti-cancer agents. The anti-cancer properties of tetrahydrocannabinol (THC), the primary psychedelic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited. The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research. The team, led by Dr Wai Liu and colleagues carried out laboratory investigations using a number of cannabinoids, either alone or in combination with each other, to measure their anti-cancer actions in relation to leukaemia. Of six cannabinoids studied, CBD, cannabigerol (CBG) and cannabigevarin (CBGV) in their neutral forms and their acid forms, each demonstrated anti-cancer properties as effective as those seen in THC. Importantly, they had an increased effect on cancer cells when combined with each other. READ MORE Cannabis Fights Cancer and Helps Manage Side Effects, Researchers FindBy Martin A. Lee, September 6th 2012 Mounting evidence shows ‘cannabinoids’ in marijuana slow cancer growth, inhibit formation of new blood cells that feed a tumor, and help manage pain, fatigue, nausea, and other side effects. Cristina Sanchez, a young biologist at Complutense University in Madrid, was studying cell metabolism when she noticed something peculiar. She had been screening brain cancer cells because they grow faster than normal cell lines and thus are useful for research purposes. But the cancer cells died each time they were exposed to tetrahydrocannabinol (THC), the principal psychoactive ingredient of marijuana. Instead of gaining insight into how cells function, Sanchez had stumbled upon the anti-cancer properties of THC. In 1998, she reported in a European biochemistry journal that THC “induces apoptosis [cell death] in C6 glioma cells,” an aggressive form of brain cancer. Subsequent peer-reviewed studies in several countries would show that THC and other marijuana-derived compounds, known as “cannabinoids,” are effective not only for cancer-symptom management (nausea, pain, loss of appetite, fatigue), they also confer a direct antitumoral effect. A team of Spanish scientists led by Manuel Guzman conducted the first clinical trial assessing the antitumoral action of THC on human beings. Guzman administered pure THC via a catheter into the tumors of nine hospitalized patients with glioblastoma, who had failed to respond to standard brain-cancer therapies. The results were published in 2006 in the British Journal of Pharmacology: THC treatment was associated with significantly reduced tumor cell proliferation in every test subject. Around the same time, Harvard University scientists reported that THC slows tumor growth in common lung cancer and “significantly reduces the ability of the cancer to spread.” What’s more, like a heat-seeking missile, THC selectively targets and destroys tumor cells while leaving healthy cells unscathed. Conventional chemotherapy drugs, by contrast, are highly toxic; they indiscriminately damage the brain and body. There is mounting evidence, according to a report in Mini-Reviews in Medicinal Chemistry, that cannabinoids “represent a new class of anticancer drugs that retard cancer growth, inhibit angiogenesis [the formation of new blood cells that feed a tumor] and the metastatic spreading of cancer cells.” READ MORE Science Shows Cannabinoids are a Good Treatment for Glioma Brain TumorsRE-Print from Norml.org Gliomas (tumors in the brain) are especially aggressive malignant forms of cancer, often resulting in the death of affected patients within one to two years following diagnosis. There is no cure for gliomas and most available treatments provide only minor symptomatic relief. A review of the modern scientific literature reveals numerous preclinical studies and one pilot clinical study demonstrating cannabinoids' ability to act as antineoplastic agents, particularly on glioma cell lines. Writing in the September 1998 issue of the journal FEBS Letters, investigators at Madrid's Complutense University, School of Biology, first reported that delta-9-THC induced apoptosis (programmed cell death) in glioma cells in culture.[1] Investigators followed up their initial findings in 2000, reporting that the administration of both THC and the synthetic cannabinoid agonist WIN 55,212-2 "induced a considerable regression of malignant gliomas" in animals.[2] Researchers again confirmed cannabinoids' ability to inhibit tumor growth in animals in 2003.[3] That same year, Italian investigators at the University of Milan, Department of Pharmacology, Chemotherapy and Toxicology, reported that the non-psychoactive cannabinoid, cannabidiol (CBD), inhibited the growth of various human glioma cell lines in vivo and in vitro in a dose dependent manner. Writing in the November 2003 issue of the Journal of Pharmacology and Experimental Therapeutics Fast Forward, researchers concluded, "Non-psychoactive CBD ... produce[s] a significant anti-tumor activity both in vitro and in vivo, thus suggesting a possible application of CBD as an antineoplastic agent."[4] READ MORE 34 Studies showing cannabis can cure cancerBy Michael Taillard June 26, 2013 There’s still a lot of confusion across the nation about whether or not marijuana is effective for cancer patients. Odds are you've heard something about it but weren't sure whether the information was reliable or definitive. So, in order to help clear things up, here is a list of 34 studies showing that marijuana cures cancer, categorized by the type of cancers being cured in each study. As you sort through the articles, note that the consistent theme between them is that marijuana shrinks tumors and selectively targets cancer cells. As bills and voter initiatives to legalize medical marijuana spread from state to state, remember that we’re not just talking about mitigating the side effects of chemo (though this is another viable use), we’re talking about curing the cancer itself as well as preventing its spread. I've taken the liberty of only including articles from credible scientific journals, removing any biased or otherwise improperly cited studies. Enjoy! READ MORE Federal Government Reports Marijuana Effective in Combatting Certain Cancers Reports ADSILOS ANGELES, March 12, 2013 (GLOBE NEWSWIRE) In a recent report, the National Cancer Institute (NCI), part of the Federal government's National Institutes of Health (NIH), stated that marijuana "inhibited the survival of both estrogen receptor–positive and estrogen receptor–negative breast cancer cell lines." The same report showed marijuana slows or stops the growth of certain lung cancer cells and suggested that marijuana may provide "risk reduction and treatment of colorectal cancer." Referring to the NCI report, Patient Rights attorney Matthew Pappas said, "The Federal government's continuing attack on people prescribed medical cannabis by their doctors is hypocritical considering the benefits reported by its own National Cancer Institute." Pappas represents patients in defending their right to reasonably obtain medical marijuana. The patients contend the Federal government and various municipalities are trying to prevent them from obtaining cannabis for medical purposes in direct contravention of state laws. "Cities that ban dispensaries are denying patients the ability to obtain a medicine the Federal government's National Institutes of Health says fights cancer and they're doing it with the Obama Administration's help." Recently, the City of Los Angeles repealed its ban of medical marijuana collectives after Bill Rosendahl, a member of its city council diagnosed with cancer and prescribed medical marijuana said to fellow council members about the ban, "You want to kill me? You want to throw me under the bus?" The NCI report also examined whether patients who smoke marijuana rather than ingesting it orally are exposed to a higher risk of lung and certain digestive system cancers. According to the government, 19 studies "failed to demonstrate statistically significant associations between marijuana inhalation and lung cancer." The report also identified a separate study of 611 lung cancer patients that showed marijuana was "not associated with an increased risk of lung cancer or other upper aerodigestive tract cancers and found no positive associations with any cancer type." In the area of prostate cancer, the NCI report was inconclusive and suggested further research was necessary. In its report, the National Cancer Institute also identified a "study of intratumoral injection of delta-9-THC in patients with recurrent glioblastoma" that showed tumor reduction in the test participants. Despite the Federal government sanctioned and authorized NCI report, Pappas said Congress and the Obama Administration have continued to thwart marijuana research. In an announced effort to displace state medical marijuana laws, the Office of National Drug Control Policy described "medical" marijuana as a "myth" fueling "troubling misconceptions" in documents found on its website. The Federal government appears to be focused on creating more chemical drugs, many of which are the subject of various attorney television commercials seeking out those adversely impacted by those drugs. Pappas said both the Drug Enforcement Administration and the Office of National Drug Control Policy continue to assert marijuana lacks any medicinal value despite the research showing cannabis reduces certain cancer risks and inhibits the growth of tumor cells. He also commented that the Federal government's anti-marijuana position contributes to and encourages prejudice and public misconception about the legitimate use of medical cannabis as treatment for seriously ill patients. READ MORE Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive CancersBy: Robin Wilkey 9/20/2012 A pair of scientists at California Pacific Medical Center in San Francisco has found that a compound derived from marijuana could stop metastasis in many kinds of aggressive cancer, potentially altering the fatality of the disease forever. "It took us about 20 years of research to figure this out, but we are very excited," said Pierre Desprez, one of the scientists behind the discovery, to The Huffington Post. "We want to get started with trials as soon as possible." The Daily Beast first reported on the finding, which has already undergone both laboratory and animal testing, and is awaiting permission for clinical trials in humans. Desprez, a molecular biologist, spent decades studying ID-1, the gene that causes cancer to spread. Meanwhile, fellow researcher Sean McAllister was studying the effects of Cannabidiol, or CBD, a non-toxic, non-psychoactive chemical compound found in the cannabis plant. Finally, the pair collaborated, combining CBD and cells containing high levels of ID-1 in a petri dish. "What we found was that his Cannabidiol could essentially 'turn off' the ID-1," Desprez told HuffPost. The cells stopped spreading and returned to normal. "We likely would not have found this on our own," he added. "That's why collaboration is so essential to scientific discovery." Cannabis Compound Destroyed Incurable Brain TumorsBy Mark Sircus Ac., OMD Oct. 10, 2012 The medical science is strongly in favor of THC laden cannabis oil as a primary cancer therapy, not just in a supportive role to control the side effects of chemotherapy. The International Medical Verities Association is putting hemp oil on its cancer protocol. It is a prioritized protocol list whose top five items are magnesium chloride, iodine, selenium, Alpha Lipoic Acid and sodium bicarbonate. It makes perfect sense to drop hemp oil right into the middle of this nutritional crossfire of anti cancer medicines, which are all available without prescription. Hemp oil has long been recognized as one of the most versatile and beneficial substances known to man. Derived from hemp seeds (a member of the achene family of fruits) it has been regarded as a superfood due to its high essential fatty acid content and the unique ratio of omega3 to omega6 and gamma linolenic acid (GLA) – 2:5:1. Hemp oil, is known to contain up to 5% of pure GLA, a much higher concentration than any other plant, even higher than spirulina. For thousands of years, the hemp plant has been used in elixirs and medicinal teas because of its healing properties and now medical science is zeroing in on the properties of its active substances. Both the commercial legal type of hemp oil and the illegal THC laden hemp oil are one of the most power-packed protein sources available in the plant kingdom. Its oil can be used in many nutritional and trans-dermal applications. In other chapters in my Winning the War on Cancer book we will discuss in-depth about GLA and cancer and also the interesting work of Dr. Johanna Budwig. She uses flax seed oil instead of hemp oil to cure cancer – through effecting changes in cell walls – using these omega3 and omega6 laden medicinal oils. Actually there is another way to use medical marijuana without smoking the leaf. According to Dr. Tod H. Mikuriya, “The usual irritating and toxic breakdown products of burning utilized with smoking are totally avoided with vaporization. Extraction and inhaling cannabinoid essential oils below ignition temperature of both crude and refined cannabis products affords significant mitigation of irritation to the oral cavity, and tracheobronchial tree from pyrollytic breakdown products. Dr. Mikuriya continues saying “The usual irritating and toxic breakdown products of burning utilized with smoking are totally avoided with vaporization. Extraction and inhaling cannabinoid essential oils below ignition temperature of both crude and refined cannabis products affords significant mitigation of irritation to the oral cavity, and tracheobronchial tree from pyrollytic breakdown products.” Harvard Study shows THC cuts tumor growth & reduces it's ability to spreadThe active ingredient in marijuana cuts tumor growth in common lung cancer in half and significantly reduces the ability of the cancer to spread, say researchers at Harvard University who tested the chemical in both lab and mouse studies. They say this is the first set of experiments to show that the compound, Δ-9 tetrahydrocannabinol (THC), inhibits EGF-induced growth and migration in epidermal growth factor receptor (EGFR) expressing non-small cell lung cancer cell lines. Lung cancers that over-express EGFR are usually highly aggressive and resistant to chemotherapy.
THC that targets cannabinoid receptors CB1 and CB2 is similar in function to endocannabinoids, which are cannabinoids that are naturally produced in the body and activate these receptors. The researchers suggest that THC or other designer agents that activate these receptors might be used in a targeted fashion to treat lung cancer. "The beauty of this study is that we are showing that a substance of abuse, if used prudently, may offer a new road to therapy against lung cancer," said Anju Preet, Ph.D., a researcher in the Division of Experimental Medicine. Acting through cannabinoid receptors CB1 and CB2, endocannabinoids (as well as THC) are thought to play a role in variety of biological functions, including pain and anxiety control, and inflammation. Although a medical derivative of THC, known as Marinol, has been approved for use as an appetite stimulant for cancer patients, and a small number of U.S. states allow use of medical marijuana to treat the same side effect, few studies have shown that THC might have anti-tumor activity, Preet says. The only clinical trial testing THC as a treatment against cancer growth was a recently completed British pilot study in human glioblastoma. In the present study, the researchers first demonstrated that two different lung cancer cell lines as well as patient lung tumor samples express CB1 and CB2, and that non-toxic doses of THC inhibited growth and spread in the cell lines. "When the cells are pretreated with THC, they have less EGFR stimulated invasion as measured by various in-vitro assays," Preet said. Then, for three weeks, researchers injected standard doses of THC into mice that had been implanted with human lung cancer cells, and found that tumors were reduced in size and weight by about 50 percent in treated animals compared to a control group. There was also about a 60 percent reduction in cancer lesions on the lungs in these mice as well as a significant reduction in protein markers associated with cancer progression, Preet says. Although the researchers do not know why THC inhibits tumor growth, they say the substance could be activating molecules that arrest the cell cycle. They speculate that THC may also interfere with angiogenesis and vascularization, which promotes cancer growth. Preet says much work is needed to clarify the pathway by which THC functions, and cautions that some animal studies have shown that THC can stimulate some cancers. "THC offers some promise, but we have a long way to go before we know what its potential is," she said. See the Harvard Study HERE Cannabis oil is a highly efficient natural cancer cureBy: Raw Michelle
September 28, 2011 Ever since the mid 70s, medical scientists have been well aware of the beneficial effects of cannabinoid compounds over cancerous cells. Thanks to modern science, over a dozen studies conducted during recent years have been able to partially reveal just how it works. Yet cannabis is still not endorsed by pharmaceutical companies as a cancer cure, and since it is not promoted through mainstream channels, very few people are aware of its benefits. Consequently, it is not sought after as an alternative to disfiguring chemotherapy and other harmful drugs. Laboratory tests conducted in 2008 by a team of scientists formed as a joint research effort between Spain, France and Italy, and published in The Journal Of Clinical Investigation, showed that the active ingredient in marijuana, known as tetrahydrocannabinol or THC, can function as a cure for brain cancer by inducing human glioma cell death through stimulation of autophagy. The study concluded that via the same biochemical process THC could terminate multiple types of cancers, affecting various cells in the body. Other studies have shown that cannabinoids may work by various mechanisms, including inhibiting cell growth, inducing cell death, and inhibiting tumor metastasis. What is amazing is that while cannabinoids effectively target and kill cancerous cells, they do not affect healthy, normal cells and may actually protect them against cellular death. Moreover, cannabinoids are also researched for their pain-modulation and anti-inflammatory abilities as they bind to special receptors in the brain, much like opioid derivatives that are commonly prescribed today. Further evidence to support the effects of cannabis extract on malignant cells comes from the real life experience of individuals who have successfully overcome cancer by using cannabis oil. Examples include a patient, who managed to completely cure his skin cancer by simply applying cannabis oil onto the affected areas of the skin, as well as another, who recovered from a severe head injury with the aid of hemp oil. One of the cannabinoids that has displayed amazing medical properties is cannabidiol, or CBD - a non-psychoactive compound that is regarded by some as the medical discovery of the 21st century, and with good reason. Research indicates that CBD can relieve convulsions, reduce inflammation, lower anxiety and suppress nausea, while also inhibiting cancer development. In addition, CBD has exhibited neuroprotective properties, relieving symptoms of dystonia and proving just as effective as regular antipsychotics in the treatment of schizophrenia. What stands out is that from the vast amount of research and data available, as well as the personal experiences of cancer survivors, is that no chemotherapy currently being used medically can match the non-toxic anti-carcinogenic and anti-tumorigenic effects of these natural plant compounds. *The story above is reprinted from materials provided by naturalnews.com Manuel Guzman shows that THC inhibited tumor growthBy: Lincoln Horsley
On February 29th 2000 a researcher in Madrid named Dr. Manuel Guzman, announced that he had been able to kill incurable brain tumors in lab rats. This was done by injecting the rats with cancer cells that produced tumors. On the twelfth day of the experiment, 15 of the rats were injected with THC only, 15 with Win-55, 212-2, a synthetic compound similar to THC and 15 were left untreated. The untreated rats died 12-18 days after the development of the tumors. The THC only treated rats lived significantly longer than the control group. Although three of the rats were unaffected by the THC, nine rats actually lived 19-35 days, while in three other rats the tumors were completely eradicated . The rats treated with Win-55,212-2 showed similar results as rats treated with THC only. One other thing the study showed was that THC is able to turn off signals that promote angiogenesis, which is the growth of new blood vessels, in the tumor. Because the tumor cannot grow new blood vessels, it cannot live. This study is over a decade old and still not talked about in the United States in the mainstream media. We need to make information like this known. Below are two links, one to a full version and one to a summrized version of "CANNABINOIDS: POTENTIAL ANTICANCER AGENTS" a report that Dr. Manuel Guzman wrote that was publised in the October 2009 issue of Nature Review. |
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